{"response":{"status":"ok","message_type":"publication"},"id":1803,"citation":"Levy et al., 2020, Phytopathology®","doi":"10.1094/phyto-07-19-0252-r","url":"https://api.seqco.de/v1/publications/1803.json","link_ext":"https://doi.org/10.1094/phyto-07-19-0252-r","title":"Lso-HPE1, an Effector of ‘\u003ci\u003eCandidatus\u003c/i\u003e Liberibacter solanacearum’, Can Repress Plant Immune Response","journal":"Phytopathology®","journal_loc":"110 (3)","journal_date":"2020-03-01","pub_type":"journal-article","abstract":"\u003cjats:p\u003e ‘Candidatus Liberibacter solanacearum’ is a plant pathogen affecting the families Solanaceae and Apiaceae in different parts of the world. ‘Ca. L. solanacearum’ is a Gram-negative, fastidious α-proteobacterium that is vectored by different psyllid species. Plant-pathogenic bacteria are known for interfering with the host physiology or defense mechanisms, often by secreting bacterial effectors. Effector proteins are critical for virulence; therefore, the identification of effectors could help with disease management. In this study, we characterized the Sec-translocon-dependent ‘Ca. L. solanacearum’–hypothetical protein effector 1 (Lso-HPE1). We compared this protein sequence in the different ‘Ca. L. solanacearum’ haplotypes. We predicted the signal peptide and validated its function using Escherichia coli’s alkaline phosphatase fusion assay. Agrobacterium tumefaciens-mediated transient expression in Nicotiana benthamiana demonstrated that Lso-HPE1 from ‘Ca. L. solanacearum’ haplotypes A and B were able to inhibit the induction of cell death in plants. We also compared gene expression of the Lso-HPE1- transcripts in ‘Ca. L. solanacearum’ haplotypes A and B in tomato and in the vector Bactericera cockerelli. This work validates the identification of a Sec-translocon-dependent ‘Ca. L. solanacearum’ protein possibly involved in suppression of plant cell death. \u003c/jats:p\u003e","long_citation_html":"Levy et al. (2020). Lso-HPE1, an Effector of ‘\u003ci\u003eCandidatus\u003c/i\u003e Liberibacter solanacearum’, Can Repress Plant Immune Response. \n\u003ci\u003ePhytopathology®\u003c/i\u003e. \u003ca href=\"https://doi.org/10.1094/phyto-07-19-0252-r\" target=\"_blank\"\u003eDOI:10.1094/phyto-07-19-0252-r\u003c/a\u003e\n","created_at":"2019-11-10T07:31:02.979Z","updated_at":"2025-11-06T13:45:47.946Z","authors":[{"id":4705,"given":"Julien G.","family":"Levy","created_at":"2019-04-15T19:27:48.949Z","updated_at":"2019-04-15T19:27:48.949Z","url":"https://api.seqco.de/v1/authors/4705.json"},{"id":6949,"given":"Rachel","family":"Gross","created_at":"2019-11-10T07:31:03.511Z","updated_at":"2019-11-10T07:31:03.511Z","url":"https://api.seqco.de/v1/authors/6949.json"},{"id":5742,"given":"Azucena","family":"Mendoza-Herrera","created_at":"2019-04-15T19:29:40.548Z","updated_at":"2019-04-15T19:29:40.548Z","url":"https://api.seqco.de/v1/authors/5742.json"},{"id":6951,"given":"Xiaotian","family":"Tang","created_at":"2019-11-10T07:31:03.994Z","updated_at":"2019-11-10T07:31:03.994Z","url":"https://api.seqco.de/v1/authors/6951.json"},{"id":6952,"given":"Kevin","family":"Babilonia","created_at":"2019-11-10T07:31:04.244Z","updated_at":"2019-11-10T07:31:04.244Z","url":"https://api.seqco.de/v1/authors/6952.json"},{"id":6953,"given":"Libo","family":"Shan","created_at":"2019-11-10T07:31:04.494Z","updated_at":"2019-11-10T07:31:04.494Z","url":"https://api.seqco.de/v1/authors/6953.json"},{"id":7135,"given":"Joseph C.","family":"Kuhl","created_at":"2020-01-12T07:30:43.971Z","updated_at":"2020-01-12T07:30:43.971Z","url":"https://api.seqco.de/v1/authors/7135.json"},{"id":7136,"given":"Margaret S.","family":"Dibble","created_at":"2020-01-12T07:30:44.184Z","updated_at":"2020-01-12T07:30:44.184Z","url":"https://api.seqco.de/v1/authors/7136.json"},{"id":6956,"given":"Fangming","family":"Xiao","created_at":"2019-11-10T07:31:05.269Z","updated_at":"2019-11-10T07:31:05.269Z","url":"https://api.seqco.de/v1/authors/6956.json"},{"id":811,"given":"Cecilia","family":"Tamborindeguy","created_at":"2019-04-15T18:46:20.062Z","updated_at":"2019-04-15T18:46:20.062Z","url":"https://api.seqco.de/v1/authors/811.json"}],"names":[{"id":34,"name":"Liberibacter solanacearum","url":"https://api.seqco.de/v1/names/34.json","uri":"https://seqco.de/i:34"}],"subjects":[{"id":5,"name":"Agronomy and Crop Science","url":"https://api.seqco.de/v1/subjects/5.json"},{"id":24,"name":"Plant Science","url":"https://api.seqco.de/v1/subjects/24.json"}]}