{"response":{"status":"ok","message_type":"publication"},"id":2858,"citation":"Davison et al., 2023, ","doi":"10.1101/2023.02.27.529723","url":"https://api.seqco.de/v1/publications/2858.json","link_ext":"https://doi.org/10.1101/2023.02.27.529723","title":"‘\u003ci\u003eCandidatus\u003c/i\u003eTisiphia’ is a widespread Rickettsiaceae symbiont in the mosquito\u003ci\u003eAnopheles plumbeus\u003c/i\u003e(Diptera: Culicidae)","journal":"","journal_loc":"","journal_date":"2023-02-27","pub_type":"posted-content","abstract":"\u003cjats:title\u003eAbstract\u003c/jats:title\u003e\u003cjats:p\u003eSymbiotic bacteria alter host biology in numerous ways, including the ability to reproduce or vector disease. Deployment of symbiont control of vector borne disease has focused on\u003cjats:italic\u003eWolbachia\u003c/jats:italic\u003einteractions with\u003cjats:italic\u003eAedes\u003c/jats:italic\u003eand is hampered in\u003cjats:italic\u003eAnopheles\u003c/jats:italic\u003eby a lack of compatible symbioses. Previous screening found the symbiont ‘\u003cjats:italic\u003eCa\u003c/jats:italic\u003e. Tisiphia’ in\u003cjats:italic\u003eAnopheles plumbeus\u003c/jats:italic\u003e, an aggressive biter and potential secondary vector of malaria parasites and West Nile virus. We screen\u003cjats:italic\u003eAn. plumbeus\u003c/jats:italic\u003esamples collected over a ten-year period across Germany and use climate databases to assess environmental influence on incidence. We find a 95% infection rate that does not fluctuate with broad environmental factors. Microscopy suggests the infection is maternally inherited based on strong localisation throughout the ovaries. Finally, we assemble a high-quality draft genome of ‘\u003cjats:italic\u003eCa\u003c/jats:italic\u003e. Tisiphia’ to explore its phylogeny and potential metabolism. This strain is closely related to those found in\u003cjats:italic\u003eCulicoides\u003c/jats:italic\u003emidges and shows similar patterns of metabolic potential.\u003cjats:italic\u003eAn. plumbeus\u003c/jats:italic\u003eprovides a viable avenue of symbiosis research in anopheline mosquitoes, which to date have one other proven infection of a heritable symbiont. Additionally, it provides future opportunity to study the impacts of ‘\u003cjats:italic\u003eCa\u003c/jats:italic\u003e. Tisiphia’ on natural and transinfected hosts, especially in relation to reproductive fitness and vector efficiency.\u003c/jats:p\u003e","long_citation_html":"Davison et al. (2023). ‘\u003ci\u003eCandidatus\u003c/i\u003eTisiphia’ is a widespread Rickettsiaceae symbiont in the mosquito\u003ci\u003eAnopheles plumbeus\u003c/i\u003e(Diptera: Culicidae). \n\u003ci\u003e\u003c/i\u003e.\n\u003ca href=\"https://doi.org/10.1101/2023.02.27.529723\" target=\"_blank\"\u003eDOI: 10.1101/2023.02.27.529723\u003c/a\u003e\n","created_at":"2023-02-28T23:00:24.570Z","updated_at":"2025-11-06T14:14:49.846Z","authors":[{"id":10353,"given":"Helen R.","family":"Davison","created_at":"2022-05-12T22:00:11.144Z","updated_at":"2022-05-12T22:00:11.144Z","url":"https://api.seqco.de/v1/authors/10353.json"},{"id":11416,"given":"Jessica","family":"Crozier","created_at":"2023-02-28T23:00:24.580Z","updated_at":"2023-02-28T23:00:24.580Z","url":"https://api.seqco.de/v1/authors/11416.json"},{"id":10355,"given":"Stacy","family":"Pirro","created_at":"2022-05-12T22:00:11.197Z","updated_at":"2022-05-12T22:00:11.197Z","url":"https://api.seqco.de/v1/authors/10355.json"},{"id":11417,"given":"Doreen","family":"Werner","created_at":"2023-02-28T23:00:24.592Z","updated_at":"2023-02-28T23:00:24.592Z","url":"https://api.seqco.de/v1/authors/11417.json"},{"id":11454,"given":"Gregory D.D.","family":"Hurst","created_at":"2023-03-09T23:00:48.569Z","updated_at":"2023-03-09T23:00:48.569Z","url":"https://api.seqco.de/v1/authors/11454.json"}],"names":[{"id":23505,"name":"Tisiphia","url":"https://api.seqco.de/v1/names/23505.json","uri":"https://seqco.de/i:23505"}],"subjects":[]}