{"response":{"status":"ok","message_type":"publication"},"id":4858,"citation":"Hrithik et al., 2026, Molecular Biology Reports","doi":"10.1007/s11033-026-12777-9","url":"https://api.seqco.de/v1/publications/4858.json","link_ext":"https://doi.org/10.1007/s11033-026-12777-9","title":"Identification and gene expression profiling of toll genes in the potato psyllid (Bactericera cockerelli) in response to ‘Candidatus liberibacter solanacearum’","journal":"Molecular Biology Reports","journal_loc":"53 (1)","journal_date":"2026-12-01","pub_type":"journal-article","abstract":"\u003cjats:title\u003eAbstract\u003c/jats:title\u003e\n                  \u003cjats:sec\u003e\n                    \u003cjats:title\u003eBackground\u003c/jats:title\u003e\n                    \u003cjats:p\u003e\n                      The Toll signaling pathway is a key component of insect innate immunity, yet its role in hemipteran vectors and their interactions with plant pathogens remains poorly understood. The potato psyllid (\n                      \u003cjats:italic\u003eBactericera cockerelli\u003c/jats:italic\u003e\n                      ), an important agricultural pest in the USA, transmits two haplotypes of\n                      \u003cjats:italic\u003e‘Candidatus\u003c/jats:italic\u003e\n                      Liberibacter solanacearum\n                      \u003cjats:italic\u003e’\u003c/jats:italic\u003e\n                      (LsoA and LsoB) that cause severe diseases in solanaceous crops.\n                    \u003c/jats:p\u003e\n                  \u003c/jats:sec\u003e\n                  \u003cjats:sec\u003e\n                    \u003cjats:title\u003eMethods and Results\u003c/jats:title\u003e\n                    \u003cjats:p\u003e\n                      We characterized Toll pathway components in the\n                      \u003cjats:italic\u003eB. cockerelli\u003c/jats:italic\u003e\n                      genome and examined their transcriptional responses during pathogen acquisition. Six Toll receptors and ten pathway-associated genes were identified in the psyllid genome. Gene expression was evaluated using RT-qPCR following exposure to the entomopathogenic fungus\n                      \u003cjats:italic\u003eBeauveria bassiana\u003c/jats:italic\u003e\n                      (Bb-490) and infection with Lso haplotypes. The transcription of five Toll receptors was significantly induced in response to\n                      \u003cjats:italic\u003eB. bassiana\u003c/jats:italic\u003e\n                      , indicating their potential role in antifungal defense. In contrast, Lso infection elicited haplotype-specific transcriptional responses: two Toll receptors (Toll like-1 and Toll-7) were up-regulated during LsoB acquisition, whereas only Toll-7 responded to LsoA. In addition, Spätzle-3 was induced by LsoB, while Spätzle was induced by LsoA. Persistent Lso infection did not significantly alter the transcriptional expression of Toll receptors.\n                    \u003c/jats:p\u003e\n                  \u003c/jats:sec\u003e\n                  \u003cjats:sec\u003e\n                    \u003cjats:title\u003eConclusions\u003c/jats:title\u003e\n                    \u003cjats:p\u003e\n                      These findings provide new insights into immune regulation in\n                      \u003cjats:italic\u003eB. cockerelli\u003c/jats:italic\u003e\n                      and highlight the potential of targeting Toll-mediated responses and fungal biocontrol strategies for sustainable disease management.\n                    \u003c/jats:p\u003e\n                  \u003c/jats:sec\u003e","long_citation_html":"Hrithik et al. (2026). Identification and gene expression profiling of toll genes in the potato psyllid (Bactericera cockerelli) in response to ‘Candidatus liberibacter solanacearum’.\n\u003ci\u003eMolecular Biology Reports\u003c/i\u003e.\n\u003ca href=\"https://doi.org/10.1007/s11033-026-12777-9\" target=\"_blank\"\u003eDOI: 10.1007/s11033-026-12777-9\u003c/a\u003e\n","created_at":"2026-09-23T00:00:25.543Z","updated_at":"2026-10-17T00:00:14.784Z","authors":[{"id":19599,"given":"Md Tafim Hossain","family":"Hrithik","created_at":"2026-09-23T00:00:25.576Z","updated_at":"2026-09-23T00:00:25.576Z","url":"https://api.seqco.de/v1/authors/19599.json"},{"id":810,"given":"Julien","family":"Levy","created_at":"2019-04-15T18:46:20.052Z","updated_at":"2019-04-15T18:46:20.052Z","url":"https://api.seqco.de/v1/authors/810.json"},{"id":19600,"given":"Taylor","family":"Hubbs","created_at":"2026-09-23T00:00:25.778Z","updated_at":"2026-09-23T00:00:25.778Z","url":"https://api.seqco.de/v1/authors/19600.json"},{"id":811,"given":"Cecilia","family":"Tamborindeguy","created_at":"2019-04-15T18:46:20.062Z","updated_at":"2019-04-15T18:46:20.062Z","url":"https://api.seqco.de/v1/authors/811.json"}],"names":[{"id":34,"name":"Liberibacter solanacearum","url":"https://api.seqco.de/v1/names/34.json","uri":"https://seqco.de/i:34"}],"subjects":[]}