{"response":{"status":"ok","message_type":"publication"},"id":4892,"citation":"Nováková et al., 2015, Applied and Environmental Microbiology","doi":"10.1128/aem.01487-15","url":"https://api.seqco.de/v1/publications/4892.json","link_ext":"https://doi.org/10.1128/aem.01487-15","title":"Arsenophonus and Sodalis Symbionts in Louse Flies: an Analogy to the Wigglesworthia and Sodalis System in Tsetse Flies","journal":"Applied and Environmental Microbiology","journal_loc":"81 (18)","journal_date":"2015-09-15","pub_type":"journal-article","abstract":"\u003cjats:title\u003eABSTRACT\u003c/jats:title\u003e\n                  \u003cjats:p\u003e\n                    Symbiosis between insects and bacteria result in a variety of arrangements, genomic modifications, and metabolic interconnections. Here, we present genomic, phylogenetic, and morphological characteristics of a symbiotic system associated with\n                    \u003cjats:named-content content-type=\"genus-species\"\u003eMelophagus ovinus\u003c/jats:named-content\u003e\n                    , a member of the blood-feeding family Hippoboscidae. The system comprises four unrelated bacteria representing different stages in symbiosis evolution, from typical obligate mutualists inhabiting bacteriomes to freely associated commensals and parasites. Interestingly, the whole system provides a remarkable analogy to the association between\n                    \u003cjats:named-content content-type=\"genus-species\"\u003eGlossina\u003c/jats:named-content\u003e\n                    and its symbiotic bacteria. In both, the symbiotic systems are composed of an obligate symbiont and two facultative intracellular associates,\n                    \u003cjats:named-content content-type=\"genus-species\"\u003eSodalis\u003c/jats:named-content\u003e\n                    and\n                    \u003cjats:named-content content-type=\"genus-species\"\u003eWolbachia\u003c/jats:named-content\u003e\n                    . In addition, extracellular\n                    \u003cjats:named-content content-type=\"genus-species\"\u003eBartonella\u003c/jats:named-content\u003e\n                    resides in the gut of\n                    \u003cjats:named-content content-type=\"genus-species\"\u003eMelophagus\u003c/jats:named-content\u003e\n                    . However, the phylogenetic origins of the two obligate mutualist symbionts differ. In\n                    \u003cjats:named-content content-type=\"genus-species\"\u003eGlossina\u003c/jats:named-content\u003e\n                    , the mutualistic\n                    \u003cjats:named-content content-type=\"genus-species\"\u003eWigglesworthia\u003c/jats:named-content\u003e\n                    appears to be a relatively isolated symbiotic lineage, whereas in\n                    \u003cjats:named-content content-type=\"genus-species\"\u003eMelophagus\u003c/jats:named-content\u003e\n                    , the obligate symbiont originated within the widely distributed\n                    \u003cjats:named-content content-type=\"genus-species\"\u003eArsenophonus\u003c/jats:named-content\u003e\n                    cluster. Although phylogenetically distant, the two obligate symbionts display several remarkably similar traits (e.g., transmission via the host's “milk glands” or similar pattern of genome reduction). To obtain better insight into the biology and possible role of the\n                    \u003cjats:named-content content-type=\"genus-species\"\u003eM. ovinus\u003c/jats:named-content\u003e\n                    obligate symbiont, “\n                    \u003cjats:named-content content-type=\"genus-species\"\u003eCandidatus\u003c/jats:named-content\u003e\n                    Arsenophonus melophagi,” we performed several comparisons of its gene content based on assignments of the Cluster of Orthologous Genes (COG). Using this criterion, we show that within a set of 44 primary and secondary symbionts, “\n                    \u003cjats:italic\u003eCa\u003c/jats:italic\u003e\n                    . Arsenophonus melophagi” is most similar to\n                    \u003cjats:named-content content-type=\"genus-species\"\u003eWigglesworthia\u003c/jats:named-content\u003e\n                    . On the other hand, these two bacteria also display interesting differences, such as absence of flagellar genes in\n                    \u003cjats:named-content content-type=\"genus-species\"\u003eArsenophonus\u003c/jats:named-content\u003e\n                    and their presence in\n                    \u003cjats:named-content content-type=\"genus-species\"\u003eWigglesworthia\u003c/jats:named-content\u003e\n                    . This finding implies that a flagellum is not essential for bacterial transmission via milk glands.\n                  \u003c/jats:p\u003e","long_citation_html":"Nováková et al. (2015). Arsenophonus and Sodalis Symbionts in Louse Flies: an Analogy to the Wigglesworthia and Sodalis System in Tsetse Flies.\n\u003ci\u003eApplied and Environmental Microbiology\u003c/i\u003e.\n\u003ca href=\"https://doi.org/10.1128/aem.01487-15\" target=\"_blank\"\u003eDOI: 10.1128/aem.01487-15\u003c/a\u003e\n","created_at":"2026-10-19T19:07:04.018Z","updated_at":"2026-10-20T00:00:21.363Z","authors":[{"id":2944,"given":"Eva","family":"Nováková","created_at":"2019-04-15T18:47:38.625Z","updated_at":"2019-04-15T18:47:38.625Z","url":"https://api.seqco.de/v1/authors/2944.json"},{"id":2943,"given":"Filip","family":"Husník","created_at":"2019-04-15T18:47:38.612Z","updated_at":"2019-04-15T18:47:38.612Z","url":"https://api.seqco.de/v1/authors/2943.json"},{"id":19745,"given":"Eva","family":"Šochová","created_at":"2026-10-19T19:07:04.074Z","updated_at":"2026-10-19T19:07:04.074Z","url":"https://api.seqco.de/v1/authors/19745.json"},{"id":2945,"given":"Václav","family":"Hypša","created_at":"2019-04-15T18:47:38.636Z","updated_at":"2019-04-15T18:47:38.636Z","url":"https://api.seqco.de/v1/authors/2945.json"}],"names":[{"id":50760,"name":"Arsenophonus melophagi","url":"https://api.seqco.de/v1/names/50760.json","uri":"https://seqco.de/i:50760"}],"subjects":[]}