{"response":{"status":"ok","message_type":"publication"},"id":4896,"citation":"Elufisan et al., 2026, ","doi":"10.21203/rs.3.rs-8476110/v1","url":"https://api.seqco.de/v1/publications/4896.json","link_ext":"https://doi.org/10.21203/rs.3.rs-8476110/v1","title":"Genome-Scale Analysis Reveals Strain Kdesi as a Distinct Evolutionary Lineage and Extensive Cryptic Diversity in the Genus Bdellovibrio","journal":"","journal_loc":"","journal_date":"2026-01-09","pub_type":"posted-content","abstract":"\u003ctitle\u003eAbstract\u003c/title\u003e\n                \u003cp\u003e\n                  \u003citalic\u003eBdellovibrio\u003c/italic\u003e\n                  are predatory bacteria with potential applications in treating multidrug-resistant bacterial infections. We isolated\n                  \u003citalic\u003eBdellovibrio\u003c/italic\u003e\n                  sp. kdesi from sewage in Reynosa, Mexico, and performed comprehensive genomic characterization. The complete genome (3,343,978bp; 48.5% GC content; 3,208 coding sequences) contains a single rRNA operon with two identical 16S rRNA genes at distinct loci. While 16S rRNA analysis showed 99.3% identity to\n                  \u003citalic\u003eB. bacteriovorus\u003c/italic\u003e\n                  SSB218315, polyphasic genomic analysis revealed kdesi as a distinct species. Core-genome phylogeny, average nucleotide identity (ANI ~ 89%), average amino acid identity (AAI ~ 82%), and digital DNA-DNA hybridization (dDDH \u0026lt; 70%) clearly demonstrated that Kdesi along with several other strains currently classified as\n                  \u003citalic\u003eB. bacteriovorus\u003c/italic\u003e\n                  represents novel genomospecies requiring formal taxonomic revision. Comparative genomic analysis of 29\n                  \u003citalic\u003eBdellovibrio\u003c/italic\u003e\n                  genomes revealed an open pan-genome (~ 25,000 genes) with limited transposable elements, absence of SecB in the Sec secretion system, and strain-specific adaptations in Type IV secretion systems. These findings underscore the need for genome-based taxonomic revision of the genus and highlight the importance of using multiple molecular criteria beyond 16S rRNA for bacterial species delineation.\n                \u003c/p\u003e","long_citation_html":"Elufisan et al. (2026). Genome-Scale Analysis Reveals Strain Kdesi as a Distinct Evolutionary Lineage and Extensive Cryptic Diversity in the Genus Bdellovibrio.\n\u003ci\u003e\u003c/i\u003e.\n\u003ca href=\"https://doi.org/10.21203/rs.3.rs-8476110/v1\" target=\"_blank\"\u003eDOI: 10.21203/rs.3.rs-8476110/v1\u003c/a\u003e\n","created_at":"2026-10-19T21:27:19.497Z","updated_at":"2026-10-20T00:00:20.707Z","authors":[{"id":19754,"given":"Temidayo Oluyomi","family":"Elufisan","created_at":"2026-10-19T21:27:19.594Z","updated_at":"2026-10-19T21:27:19.594Z","url":"https://api.seqco.de/v1/authors/19754.json"},{"id":19755,"given":"Isabel Cristina","family":"Rodríguez-Luna","created_at":"2026-10-19T21:27:19.612Z","updated_at":"2026-10-19T21:27:19.612Z","url":"https://api.seqco.de/v1/authors/19755.json"},{"id":19756,"given":"Yewande Olajumoke","family":"Ajao","created_at":"2026-10-19T21:27:19.625Z","updated_at":"2026-10-19T21:27:19.625Z","url":"https://api.seqco.de/v1/authors/19756.json"},{"id":19757,"given":"Ibukun John","family":"Abulude","created_at":"2026-10-19T21:27:19.638Z","updated_at":"2026-10-19T21:27:19.638Z","url":"https://api.seqco.de/v1/authors/19757.json"},{"id":19758,"given":"Alejandro","family":"Sánchez-Varela","created_at":"2026-10-19T21:27:19.650Z","updated_at":"2026-10-19T21:27:19.650Z","url":"https://api.seqco.de/v1/authors/19758.json"},{"id":19759,"given":"Omotayo Opemipo","family":"Oyedara","created_at":"2026-10-19T21:27:19.662Z","updated_at":"2026-10-19T21:27:19.662Z","url":"https://api.seqco.de/v1/authors/19759.json"},{"id":19760,"given":"Ronald","family":"Ferrera-Cerrato","created_at":"2026-10-19T21:27:19.673Z","updated_at":"2026-10-19T21:27:19.673Z","url":"https://api.seqco.de/v1/authors/19760.json"},{"id":19761,"given":"Miguel Angel","family":"Villaloboz_Lopez","created_at":"2026-10-19T21:27:19.685Z","updated_at":"2026-10-19T21:27:19.685Z","url":"https://api.seqco.de/v1/authors/19761.json"},{"id":19762,"given":"Xianwu","family":"Guo","created_at":"2026-10-19T21:27:19.696Z","updated_at":"2026-10-19T21:27:19.696Z","url":"https://api.seqco.de/v1/authors/19762.json"}],"names":[],"subjects":[]}